The LOV Domain Family: Photoresponsive Signaling Modules Coupled to Diverse Output Domains

Here, we review the properties of the light, oxygen, or voltage (LOV) family of blue-light photoreceptor domains, a subset of the Per-ARNT-Sim (PAS) superfamily. These flavin-binding domains, first identified in the higher-plant phototropins, are now shown to be present in plants, fungi, and bacteria. Notably, LOV domains are coupled to a wide array of other domains, including kinases, phosphodiesterases, F-box domains, STAS domains, and zinc fingers, which suggests that the absorption of blue light by LOV domains regulates the activity of these structurally and functionally diverse domains.
The LOV Domain Family: Photoresponsive Signaling Modules Coupled to Diverse Output Domains

ooo[clip]ooo

ooo[bioinfo]ooo

ooo[funny-gene]ooo