Monday, July 31, 2006

A genomic code for nucleosome positioning -- Nature

Computational biology makes it to the NY Times! -- for analysis of chromatin structure. Wonder the degree to which this analysis applies to human encode data.

ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16862119&query_hl=5&itool=pubmed_docsum
Nature. 2006 Jul 19;
A genomic code for nucleosome positioning.

Scientists Say They’ve Found a Code Beyond Genetics in DNA
By NICHOLAS WADE, Published: July 25, 2006
nytimes.com/2006/07/25/science/25dna.html
Researchers believe they have found a second code in DNA in addition to the genetic code. The genetic code specifies all the proteins that a cell makes. The second code, superimposed on the first, sets the placement of the nucleosomes, miniature protein spools around which the DNA is looped. The spools both protect and control access to the DNA itself....
ooo[clip]ooo ooo[bioinfo]ooo ooo[intergenic]ooo